INTRODUCTION AND OBJECTIVES: Lower blood eosinophil counts have been associated with increased mechanical ventilation rates in patients with community-acquired pneumonia (CAP). However, the optimal eosinophil count threshold for identifying CAP patients at high risk of respiratory failure remains undefined. This study aimed to establish an optimal admission eosinophil count as a prognostic biomarker for respiratory failure in CAP. METHODS: This prospective, multicentre cohort study (PROGRESS) enrolled adult patients (
- Weckler, B. C.
- Martin, R.
- Kutzinski, M.
- Bertrams, W.
- Jung, A. L.
- Pott, H.
- Laakmann, K.
- Schulte, L.
- Ahnert, P.
- Heider, D.
- Ringshandl, S.
- Seidemann, C.
- Suttorp, N.
- Witzenrath, M.
- Wildberg, C.
- Lehmann, M.
- Rohde, G.
- Greulich, T.
- Vogelmeier, C. F.
- Schmeck, B.
Keywords
- Humans
- *Community-Acquired Infections/complications/blood
- Male
- Female
- Prospective Studies
- *Respiratory Insufficiency/etiology/blood/diagnosis/therapy
- *Eosinophils
- Aged
- Middle Aged
- *Pneumonia/complications/blood
- Leukocyte Count
- Respiration, Artificial/statistics & numerical data
- Prognosis
- Length of Stay/statistics & numerical data
- Biomarkers/blood
- Intensive Care Units/statistics & numerical data
- Predictive Value of Tests
- ROC Curve
- Glucocorticoids/therapeutic use
- Adult
- Community-Acquired Pneumonia
- Pneumonia
- biomarker
- blood eosinophil count
- risk stratification
