Impaired respiratory variation of right atrial pressure (RAP) in severe pulmonary hypertension (PH) suggests difficulty tolerating increased preload during inspiration. Our study explores whether this impairment links to specific factors: right ventricular (RV) diastolic function, elevated RV afterload, systolic RV function, or RV-pulmonary arterial (PA) coupling. We retrospectively evaluated respiratory RAP variation in all participants enrolled in the EXERTION study. Impaired respiratory variation was defined as end-expiratory RAP - end-inspiratory RAP
- Yogeswaran, A.
- da Rocha, B. B.
- Rako, Z. A.
- Kaufmann, S. J.
- Schäfer, S.
- Kremer, N.
- Ghofrani, H. A.
- Seeger, W.
- Tello, K.
Keywords
- Humans
- Female
- Male
- *Hypertension, Pulmonary/physiopathology
- Middle Aged
- *Atrial Pressure
- Retrospective Studies
- Aged
- Ventricular Function, Right/physiology
- Conductance catheterization
- Diastolic dysfunction
- End-diastolic elastance
- Exercise haemodynamics
- Prognosis
- Pulmonary hypertension
- Respiratory variation
- Retrospective analysis
- Right atrial pressure
- Right ventricular dysfunction
