Elafin expression is regulated by CFTR-mutation and TGF

BACKGROUND: Cystic Fibrosis (CF) lung disease is characterized by inflammation and progressive matrix remodeling. These processes are influenced by genetic modifiers such as Transforming Growth Factor

  • Thomassen, J. C.
  • Vohlen, C.
  • Rietschel, E.
  • Alcazar, M. A. A.
  • van Koningsbruggen-Rietschel, S.

Keywords

  • CFTR-mutation
  • Elafin
  • Homeostasis of proteases
  • Human bronchial epithelial cells
  • Inflammation
  • Neutrophile elastase
  • Tgfβ1
Publication details
DOI: 10.1016/j.jcf.2025.08.016
Journal: J Cyst Fibros
Work Type: Original
Access number: 40947321
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